Peroxiredoxin 2 antibody (C-Term)

Catalog No. ABIN374698

Product Details anti-Peroxiredoxin 2 Antibody

Target: Peroxiredoxin 2 (PRDX2)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-NVDDSKEYFS KHN

Specificity: This antibody is expected to recognise isoforms a and b of Peroxiredoxin 2 only.

Cross-Reactivity (Details): Species reactivity (expected):Rat.
Species reactivity (tested):Human, Mouse.

Purification: Affinity Chromatography

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_005800.3, NP_859427.1.

Application Details

Application Notes: ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % Sodium Azide, pH ~7.3 with 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Peroxiredoxin 2

Target: Peroxiredoxin 2 (PRDX2)

Alternative Name: Peroxiredoxin-2 / PRDX2 (PRDX2 Products)

Synonyms: NKEF-B antibody, NKEFB antibody, PRP antibody, PRX2 antibody, PRXII antibody, PTX1 antibody, TDPX1 antibody, TPX1 antibody, TSA antibody, AL022839 antibody, Band-8 antibody, NkefB antibody, PrxII antibody, TDX1 antibody, TPx antibody, TPx-B antibody, TR antibody, Tdpx1 antibody, Torin antibody, nkefb antibody, prx-2 antibody, prx2 antibody, prxii antibody, tdpx1 antibody, tpx1 antibody, peroxiredoxin 2 antibody, peroxiredoxin 2 L homeolog antibody, PRDX2 antibody, Prdx2 antibody, prdx2.L antibody

Background: The Peroxiredoxin (Prdx, Prx, or TrxPx) family of enzymes is a recently identified family of peroxidases found in free living organisms. The six known isoforms (Prx1 to 6) play an important role in protecting lipids, enzymes and DNA against peroxides, such as hydrogen peroxide. The ubiquitously expressed peroxiredoxins have also been shown to play a role in apoptosis and cell differentiation. This is acomplished by the active cysteine of Prx reducing peroxides, which is then converted into a transient cysteine sulfenic acid or cysteine sulfinic acid. If Prx protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer.Synonyms: NKEF-B, NKEFB, Natural killer cell-enhancing factor B, PRDX-2, PRP, Prx-2, Prx2, TDPX1, TSA, Thiol-specific antioxidant protein, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1

Gene ID: 7001, 9606

UniProt: P32119