Neurexin 1 antibody (C-Term)

Catalog No. ABIN783000

Product Details anti-Neurexin 1 Antibody

Target: Neurexin 1 (NRXN1)

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This Neurexin 1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-KEKQPSSAKS SNKN

Specificity: This antibody is expected to recognise both reported isoforms (NP_004792.1 and NP_620072.1).

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_004792.1 , NP_620072.1. Genename: NRXN1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Neurexin 1

Target: Neurexin 1 (NRXN1)

Alternative Name: Neurexin 1 alpha (NRXN1 Products)

Synonyms: Hs.22998 antibody, PTHSL2 antibody, SCZD17 antibody, CG7050 antibody, CT21808 antibody, Dmel\\CG7050 antibody, Nrx antibody, Nrx1 antibody, dnrx antibody, dnrx-1 antibody, nrx antibody, Nrxn1b antibody, NRXN1 antibody, Nrx-1 antibody, GB13455 antibody, GB18754 antibody, 1700062G21Rik antibody, 9330127H16Rik antibody, A230068P09Rik antibody, mKIAA0578 antibody, neurexin 1 antibody, Neurexin 1 antibody, neurexin I antibody, neurexin 1b antibody, neurexin 1a antibody, NRXN1 antibody, Nrx-1 antibody, Nrxn1 antibody, nrxn1 antibody, nrxn1b antibody, nrxn1a antibody

Background: Neurexins are components of septate junctions playing a role in cell adhesion, in vertebrates they are components of synapses, playing a potential role in axon guidance and innervation. Neurexin functions in the establishment of an association of the internal cytoskeleton with the cell surface, and can function, at least in vertebrates, in transducing extracellular events to the inside of the cell via a specialized intracellular kinase.Synonyms: NRXN1

Gene ID: 9378

NCBI Accession: NP_001129131

UniProt: Q9ULB1

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development