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UCP2 antibody (Internal Region)

UCP2 Reactivity: Human, Mouse, Rat, Dog WB, ELISA Host: Goat Polyclonal unconjugated
Catalog No. ABIN374813
  • Target See all UCP2 Antibodies
    UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))
    Binding Specificity
    • 16
    • 15
    • 15
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    Human, Mouse, Rat, Dog
    Host
    • 73
    • 7
    • 1
    • 1
    Goat
    Clonality
    • 77
    • 5
    Polyclonal
    Conjugate
    • 27
    • 12
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This UCP2 antibody is un-conjugated
    Application
    • 75
    • 39
    • 39
    • 18
    • 18
    • 17
    • 10
    • 9
    • 9
    • 5
    • 3
    • 2
    Western Blotting (WB), ELISA
    Sequence
    C-DSVKQFYTKG SEH
    Specificity
    This antibody recognizes Uncoupling protein 2 / UCP2. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse, Rat, Canine (Dog).
    Purification
    Immunoaffinity Chromatography
    Immunogen
    Synthetic peptide from from the internal region of Human UCP2 (NP_003346.2). Genename: UCP2
    Top Product
    Discover our top product UCP2 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/4000. Western Blot: 0.2 - 1 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Tris buffered saline, pH~7.3 0.02% Sodium Azide 0.5% BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
    Expiry Date
    12 months
  • Liu, Shim, Nguyen, Gibbons, Mitchell, Poirier: "Tempol protects cardiomyocytes from nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 139, Issue 1, pp. 133-41, (2014) (PubMed).

  • Target
    UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))
    Alternative Name
    SLC25A8 / UCP2 (UCP2 Products)
    Synonyms
    UCP2 antibody, DKFZp470P1633 antibody, ucp2 antibody, MGC53319 antibody, MGC75881 antibody, cb74 antibody, ATUCP2 antibody, K19M22.21 antibody, K19M22_21 antibody, uncoupling protein 2 antibody, BMIQ4 antibody, SLC25A8 antibody, UCPH antibody, Slc25a8 antibody, mitochondrial uncoupling protein 2 antibody, uncoupling protein 2 antibody, uncoupling protein 2 (mitochondrial, proton carrier) L homeolog antibody, uncoupling protein 2 (mitochondrial, proton carrier) antibody, uncoupling protein 1 antibody, PTRG_09289 antibody, UCP2 antibody, LOC100282746 antibody, ucp2.L antibody, ucp2 antibody, ucp1 antibody, Ucp2 antibody
    Background
    UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. UCP2 gene is expressed in many tissues, with the greatest expression in skeletal muscle. UCP2 is thought to play a role in non shivering thermogenesis, obesity and diabetes.
    Alternate names: Mitochondrial uncoupling protein 2, Solute carrier family 25 member 8, UCP 2, UCP-2, UCPH
    Gene ID
    7351, 9606
    UniProt
    P55851
    Pathways
    Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Proton Transport
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