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ROBO3 antibody (Internal Region)

ROBO3 Reactivity: Human WB, EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN374821
  • Target See all ROBO3 Antibodies
    ROBO3 (Roundabout, Axon Guidance Receptor, Homolog 3 (ROBO3))
    Binding Specificity
    • 3
    • 3
    • 2
    • 1
    • 1
    Internal Region
    Reactivity
    • 21
    • 5
    • 3
    • 3
    • 3
    • 1
    Human
    Host
    • 16
    • 4
    • 4
    Goat
    Clonality
    • 22
    • 2
    Polyclonal
    Conjugate
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ROBO3 antibody is un-conjugated
    Application
    • 15
    • 13
    • 5
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Sequence
    C-RRKQRKELSH YT
    Specificity
    This antibody detects ROBO3/RIG1 (internal).
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    Immunogen
    Peptide with sequence from the internal region of the protein sequence Genename: ROBO3
    Top Product
    Discover our top product ROBO3 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/32000. Western Blot: 0.5 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ROBO3 (Roundabout, Axon Guidance Receptor, Homolog 3 (ROBO3))
    Alternative Name
    ROBO3 (ROBO3 Products)
    Synonyms
    HGPPS antibody, HGPS antibody, RBIG1 antibody, RIG1 antibody, CG14345 antibody, CT17158 antibody, Robo-3 antibody, Robo3 antibody, dRobo-3 antibody, DmelCG5423 antibody, CG5423 antibody, ROBO3 antibody, robo3 antibody, DKFZp468G0223 antibody, Rbig1 antibody, Rig-1 antibody, Rig1 antibody, Robo3a antibody, Robo3b antibody, cb503 antibody, roundabout guidance receptor 3 antibody, roundabout 3 antibody, robo3 antibody, roundabout guidance receptor 3 L homeolog antibody, roundabout, axon guidance receptor, homolog 3 (Drosophila) antibody, ROBO3 antibody, robo3 antibody, Robo3 antibody, LOC658818 antibody, robo3.L antibody
    Background
    Roundabout proteins 1-3, known as Robo1-3, are repulsive axon guidance receptors that bind to Slit, a repellent secreted by midline glia during development. Robo3 (also known as Rig1) is important for normal axon navigation at the ventral midline of the neural tube during development and is specifically expressed by commissural axons in rodents. Loss-of-function studies in mice show that Robo3 is required to allow commissural axons to enter the floor plate and cross to the contralateral side of the spinal cord. Some isoforms of Robo3 exist.Synonyms: ROBO-3, Roundabout homolog 3, Roundabout-like protein 3
    Molecular Weight
    148kDa (NP_071765.2).
    Gene ID
    64221, 9606
    UniProt
    Q96MS0
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