DGAT2 antibody (C-Term, Internal Region)

Catalog No. ABIN374843

Product Details anti-DGAT2 Antibody

Target: DGAT2 (Diacylglycerol O-Acyltransferase 2 (DGAT2))

Binding Specificity: C-Term, Internal Region

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This DGAT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequence: C-KLEHPTQQDI DLYH

Specificity: This antibody recognizes DGAT2 and is not expected to cross-react with other DGAT members.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog).
Species reactivity (tested):Human.

Purification: Affinity Chromatography

Immunogen: Synthetic peptide (C-KLEHPTQQDIDLYH) from the internal region (near the C Terminus) of Human Genename: DGAT2

Application Details

Application Notes: Peptide ELISA: 1/128000. Western Blot: 0.3 - 1 μg/mL. Immunohistochemistry on paraffin sections: 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DGAT2

Target: DGAT2 (Diacylglycerol O-Acyltransferase 2 (DGAT2))

Alternative Name: DGAT2 (DGAT2 Products)

Synonyms: ARAT antibody, GS1999FULL antibody, hmfn1045 antibody, 0610010B06Rik antibody, DGAT-2 antibody, zgc:113394 antibody, DDBDRAFT_0188804 antibody, DDBDRAFT_0233097 antibody, DDB_0188804 antibody, DDB_0233097 antibody, diacylglycerol O-acyltransferase 2 antibody, diacylglycerol O-acyltransferase 2 L homeolog antibody, diacylglycerol acyltransferase family antibody, DGAT2 antibody, dgat2 antibody, Dgat2 antibody, dgat2.L antibody

Background: DGAT2 is an essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. It is required for synthesis and storage of intracellular triglycerides. It probably plays a central role in cytosolic lipid accumulation.Synonyms: DGAT-2, Diacylglycerol O-acyltransferase 2, Diglyceride acyltransferase 2, EC=2.3.1.20

Molecular Weight: 43.8 kDa (NP_115953.2).

Gene ID: 84649

NCBI Accession: NP_115953

UniProt: Q96PD7