IGFBP4 antibody (C-Term)

Catalog No. ABIN374952

Product Details anti-IGFBP4 Antibody

Target: IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This IGFBP4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to IGFBP4.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence KGELDCHQLADSFRE, from the C Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/8000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IGFBP4

Target: IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))

Alternative Name: IGFBP4 (IGFBP4 Products)

Synonyms: IGFBP4 antibody, igfbp4 antibody, BP-4 antibody, HT29-IGFBP antibody, IBP4 antibody, IGFBP-4 antibody, AI875747 antibody, Deb2 antibody, IGF-BP4 antibody, IBP-4 antibody, insulin like growth factor binding protein 4 antibody, insulin-like growth factor-binding protein 4 antibody, insulin-like growth factor binding protein 4 antibody, IGFBP4 antibody, LOC100136305 antibody, LOC100194498 antibody, igfbp4 antibody, Igfbp4 antibody

Background: IGFBP4 (Insulin like growth factor binding protein 4) is produced from a DNA sequence encoding the human IGFBP4 protein. Mature human IGFBP4 has a calculated molecular mass of approximately 26 kDa. Due to glycosylation, the recombinant protein migrates as a 32 kDa and 25 kDa protein under reducing and non reducing conditions, respectively. Human IGFBP4 has a potential N-linked glycosylation site and shares approximately 90 % amino acid sequence identity with both mouse and rat IGFBP4. IGFBP4 is a member of the superfamily of insulin-like growth factor (IGF) binding proteins which include six high affinity IGF binding proteins (IGFBP) and at least four low affinity binding proteins referred to as IGFBP related proteins (IGFBPrP). IGFBP4 functions as an inhibitor of IGF action and its main function may be to protect cells from overstimulation by IGFs or to allow activation of alternate transmembrane signaling pathways that are inhibited by IGF exposure. IGFBP4 is expressed in multiple tissues including adrenal, testis, spleen, heart, lung, kidney, liver, stomach, hypothalamus, and brain cortex.Synonyms: IBP-4, IBP4, IGF-binding protein 4, IGFBP-4, Insulin-like growth factor-binding protein 4

Gene ID: 3487

NCBI Accession: NP_001543

UniProt: P22692

Pathways: WNT Signaling, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process