DACH2 antibody (Internal Region)

Catalog No. ABIN375188

Product Details anti-DACH2 Antibody

Target: DACH2 (Dachshund 2 (DACH2))

Binding Specificity: Internal Region

Reactivity: Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This DACH2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to Dachshund homolog 2.

Cross-Reactivity (Details): Species reactivity (expected):Human.
Species reactivity (tested):Mouse.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography

Immunogen: Peptide with sequence C-TRKQAVNSSRPGR, from the internal region of the protein sequence

Application Details

Application Notes: ELISA: 1/64000. Western Blot: 0.03 - 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for DACH2

Target: DACH2 (Dachshund 2 (DACH2))

Alternative Name: DACH2 (DACH2 Products)

Synonyms: 9430028N04Rik antibody, RGD1561687 antibody, dachshund family transcription factor 2 antibody, dachshund 2 (Drosophila) antibody, dachshund family transcription factor 2 L homeolog antibody, dachshund homolog 2 antibody, dachshund homolog 2 (Drosophila) antibody, DACH2 antibody, Dach2 antibody, dach2.L antibody, LOC612847 antibody, dach2 antibody

Background: DACH2 is a transcription factor that is involved in regulation of organogenesis. It seems to be a regulator for SIX1 and SIX6 and may act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. It probably binds to DNA via its DACH box-N domain.Synonyms: DACH-2, Dachshund homolog 2

Gene ID: 117154

NCBI Accession: NP_001136042

UniProt: Q925Q8