ALDH3A2 antibody (Internal Region)

Catalog No. ABIN498085

Product Details anti-ALDH3A2 Antibody

Target: ALDH3A2 (Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2))

Binding Specificity: Internal Region

Reactivity: Rat, Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This ALDH3A2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-KGLKGESVNK LRY

Specificity: This antibody is expected to recognize both reported isoforms (NP_001026976.1, NP_000373.1).

Cross-Reactivity (Details): Species reactivity (tested):Mouse, Rat.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_113919.2. Genename: Aldh3a2

Application Details

Application Notes: Peptide ELISA: Detection Limit: 1/32000. Western blot: 0.03-0.1 μg/mL. Detects a band of Approx 55 kDa in Mouse and Rat Liver lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ALDH3A2

Target: ALDH3A2 (Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2))

Alternative Name: ALDH3A2 / ALDH10 (ALDH3A2 Products)

Synonyms: ALDH10 antibody, FALDH antibody, SLS antibody, AI194803 antibody, Ahd-3 antibody, Ahd-3r antibody, Ahd3 antibody, Ahd3-r antibody, Aldh4 antibody, Aldh4-r antibody, ALDH-III antibody, CG11140 antibody, CT41571 antibody, Dhap antibody, Dmel\\CG11140 antibody, l(2)03610 antibody, Aldh-III antibody, aldh3a2 antibody, wu:fc06b11 antibody, zgc:92064 antibody, ALDH3A2 antibody, aldehyde dehydrogenase 3 family member A2 antibody, aldehyde dehydrogenase family 3, subfamily A2 antibody, aldehyde dehydrogenase 3 family, member A2 antibody, Aldehyde dehydrogenase type III antibody, fatty aldehyde dehydrogenase antibody, aldehyde dehydrogenase 3 family, member A2a antibody, aldehyde dehydrogenase 3 family member A2 S homeolog antibody, aldH antibody, ALDH3A2 antibody, Aldh3a2 antibody, Aldh-III antibody, PTRG_02589 antibody, aldh3a2 antibody, aldh3a2a antibody, aldh3a2.S antibody, aldH antibody

Background: ALDH3A2 also known as Aldehyde dehydrogenase 10 or FALDH, catalyses the oxidation of long-chain fatty aliphatic aldehydes to fatty acids. Its substrate specificity includes a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbon atoms in length. Some mutations in the ALDH3A2 gene result in Sjoegren-Larsson Syndrome, a neurocutaneous disorder that is characterised by mental retardation (IQ less than 60), spastic di- or tetraplegia and congenital ichthyosis (increased keratinisation). Altered ALDH3A2 gene expression levels are associated with Fetal Alcohol Spectrum Disorders.Synonyms: Aldehyde dehydrogenase 10, Aldehyde dehydrogenase family 3 member A2, FALDH, Fatty aldehyde dehydrogenase, Microsomal aldehyde dehydrogenase

Gene ID: 65183

NCBI Accession: NP_113919

UniProt: P30839