Receptor Accessory Protein 4 antibody (Center)

Catalog No. ABIN783584

Product Details anti-Receptor Accessory Protein 4 Antibody

Target: Receptor Accessory Protein 4 (REEP4)

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Receptor Accessory Protein 4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the center of human REEP4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for Receptor Accessory Protein 4

Target: Receptor Accessory Protein 4 (REEP4)

Alternative Name: REEP4 (REEP4 Products)

Synonyms: C8orf20 antibody, 2700029E10Rik antibody, RGD1306561 antibody, receptor accessory protein 4 antibody, REEP4 antibody, Reep4 antibody

Background: Mammalian odorant receptors require accessory proteins such as RTP1 and RTP2 for functional cell surface expression. Receptor expression-enhancing protein (REEP) family members are transmembrane proteins which interact with odorant receptor proteins and may enhance the odorant receptor responses to odorants. Recently studies have shown other chemosensory receptors such as bitter taste receptors are also influenced by RTP and REEP family members. In studies in Xenopus RNAi to reduce REEP4 levels, embryos showed a slightly kinked body axis and were paralyzed. Further analysis revealed downregulated levels of several neural and muscle markers, suggesting the REEP4 may play a role in the maintenance of both the nervous system and musculature.Synonyms: C8orf20, Receptor expression-enhancing protein 4

Gene ID: 80346

NCBI Accession: NP_079508

UniProt: Q9H6H4