SLC39A12 antibody (N-Term)

Catalog No. ABIN783813

Product Details anti-SLC39A12 Antibody

Target: SLC39A12 (Solute Carrier Family 39 (Zinc Transporter), Member 12 (SLC39A12))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC39A12 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Zinc transporter ZIP12 / SLC39A12 at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the amino terminus of human ZIP12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for SLC39A12

Target: SLC39A12 (Solute Carrier Family 39 (Zinc Transporter), Member 12 (SLC39A12))

Alternative Name: Zinc Transporter ZIP12 / SLC39A12 (SLC39A12 Products)

Synonyms: LZT-Hs8 antibody, ZIP-12 antibody, bA570F3.1 antibody, AW046938 antibody, Gm731 antibody, solute carrier family 39 member 12 antibody, solute carrier family 39 (zinc transporter), member 12 antibody, SLC39A12 antibody, Slc39a12 antibody, slc39a12 antibody

Background: The zinc transporter ZIP12, also known as SLC39A12, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP12 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Increased levels of ZIP12 have been observed during acute inflammation in the airway and asthma, suggesting that it may be promote increased zinc uptake, as this can reduce inflammation. The zinc content in brains in individuals with schizophrenia is lower than in individuals with other cerebral diseases, and mutations in ZIP12 have been observed in a small group of schizophrenic patients, suggesting that ZIP12 may play a role in this disease.Synonyms: LIV-1 subfamily of ZIP zinc transporter 8, LZT-Hs8, Solute carrier family 39 member 12, ZIP-12, ZIP12, Zrt-and Irt-like protein 12

Gene ID: 221074

NCBI Accession: NP_001138667

UniProt: Q504Y0