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ESX Homeobox 1 antibody (Center)

ESX1 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499804
  • Target See all ESX Homeobox 1 (ESX1) Antibodies
    ESX Homeobox 1 (ESX1)
    Binding Specificity
    • 9
    • 8
    • 6
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 18
    • 3
    Human
    Host
    • 19
    • 1
    Rabbit
    Clonality
    • 20
    Polyclonal
    Conjugate
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    This ESX Homeobox 1 antibody is un-conjugated
    Application
    • 20
    • 15
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    ESX1 antibody was raised against a 19 amino acid peptide near the center of human ESX1.
    Isotype
    IgG
    Top Product
    Discover our top product ESX1 Primary Antibody
  • Application Notes
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Target
    ESX Homeobox 1 (ESX1)
    Alternative Name
    ESX1 (ESX1 Products)
    Synonyms
    ESX1L antibody, ESXR1 antibody, Spx1 antibody, ESX homeobox 1 antibody, extraembryonic, spermatogenesis, homeobox 1 antibody, ESX1 antibody, Esx1 antibody
    Background
    Homeobox proteins are transcription factors that contain a helix-turn-helix DNA binding domain termed the homeodomain. ESX1 is an X-linked homeobox gene primarily expressed in the placenta and testis and contains two functional domains: the homeodomain and the proline-rich domain. During embryogenesis, ESX1 is expressed in the extraembryonic tissues, including the endoderm of the visceral yolk sac, the ectoderm of the chorion and the labyrinthine trophoblast of the chorioallantoic placenta. ESX1 can act like a transcriptional repressor to the human oncogene K-ras and treatment of human cancer cells with an ESX1 protein fragment containing the homeodomain reduces the tumorgenicity of cells containing oncogenic K-ras mutations, suggesting ESX1 may be useful as a therapeutic treatment for these cancers.Synonyms: ESX1L, ESX1R, Homeobox protein ESX1
    Gene ID
    80712
    UniProt
    Q8N693
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