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SEC16B antibody (C-Term)

SEC16B Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500212
  • Target See all SEC16B Antibodies
    SEC16B (SEC16 Homolog B (SEC16B))
    Binding Specificity
    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 28
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 27
    • 1
    Rabbit
    Clonality
    • 28
    Polyclonal
    Conjugate
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SEC16B antibody is un-conjugated
    Application
    • 22
    • 13
    • 13
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Cross-Reactivity (Details)
    Species reactivity (tested):Humna, Mouse, Rat
    Purification
    Peptide affinity chromatography
    Immunogen
    LZTR2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LZTR2.
    Isotype
    IgG
    Top Product
    Discover our top product SEC16B Primary Antibody
  • Application Notes
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Target
    SEC16B (SEC16 Homolog B (SEC16B))
    Alternative Name
    SEC16B (SEC16B Products)
    Synonyms
    LZTR2 antibody, PGPR-p117 antibody, RGPR antibody, SEC16S antibody, Lztr2 antibody, Rgpr antibody, Rgpr-p117 antibody, RGPR-p117 antibody, SEC16 homolog B, endoplasmic reticulum export factor antibody, SEC16 homolog B (S. cerevisiae) antibody, SEC16B antibody, sec16b antibody, Sec16b antibody
    Background
    LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.Synonyms: KIAA1928, LZTR2, Leucine zipper transcription regulator 2, Protein SEC16 homolog B, Protein transport protein Sec16B, RGPR, RGPR-p117, Regucalcin gene promoter region-related protein p117, SEC16B, SEC16S
    Gene ID
    89866
    NCBI Accession
    NP_149118
    UniProt
    Q96JE7
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