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Neurotrypsin antibody (N-Term)

PRSS12 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500334
  • Target See all Neurotrypsin (PRSS12) Antibodies
    Neurotrypsin (PRSS12) (Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12))
    Binding Specificity
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 10
    • 2
    Rabbit
    Clonality
    • 11
    • 1
    Polyclonal
    Conjugate
    • 8
    • 2
    • 1
    • 1
    This Neurotrypsin antibody is un-conjugated
    Application
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects Neurotrypsin at N-term.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    Neurotrypsin antibody was raised against a 23 amino acid peptide from near the amino terminus of human neurotrypsin.
    Isotype
    IgG
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  • Application Notes
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    Neurotrypsin (PRSS12) (Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12))
    Alternative Name
    Neurotrypsin (PRSS12 Products)
    Synonyms
    PRSS12 antibody, BSSP-3 antibody, BSSP3 antibody, MRT1 antibody, Bssp-3 antibody, motopsin antibody, Nt antibody, protease, serine 12 antibody, 26S proteasome regulatory SU antibody, prsS12 antibody, neurotrypsin antibody, protease, serine 12 neurotrypsin (motopsin) antibody, PRSS12 antibody, prsS12 antibody, HAN_3g451 antibody, CpipJ_CPIJ005457 antibody, CpipJ_CPIJ005852 antibody, Prss12 antibody
    Background
    Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.Synonyms: Leydin, Motopsin, PRSS12, Serine protease 12
    Gene ID
    8492
    UniProt
    P56730
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