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CD180 antibody (C-Term)

CD180 Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500626
  • Target See all CD180 Antibodies
    CD180 (CD180 Molecule (CD180))
    Binding Specificity
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 19
    • 8
    • 3
    • 1
    Human, Mouse
    Host
    • 11
    • 8
    • 2
    Rabbit
    Clonality
    • 11
    • 10
    Polyclonal
    Conjugate
    • 16
    • 2
    • 2
    • 1
    This CD180 antibody is un-conjugated
    Application
    • 11
    • 11
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects CD180 / RP105 at C-term).
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse
    Purification
    Peptide affinity chromatography
    Immunogen
    RP105 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human RP105.
    Isotype
    IgG
    Top Product
    Discover our top product CD180 Primary Antibody
  • Application Notes
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    CD180 (CD180 Molecule (CD180))
    Alternative Name
    CD180 / RP105 (CD180 Products)
    Synonyms
    Ly78 antibody, CD180 antibody, LY64 antibody, RP105 antibody, F630107B15 antibody, CD180 molecule antibody, CD180 antigen antibody, Cd180 antibody, CD180 antibody
    Background
    Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins. One such protein is RP105, a recently identified homolog to TLR4 that, with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. It has also been suggested that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes. Despite its predicted molecular weight, RP105 often migrates at 95 - 105 kDa.Synonyms: LY64, Lymphocyte antigen 64, Radioprotective 105 kDa protein
    Gene ID
    4064
    UniProt
    Q99467
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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