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TXNDC11 antibody (Internal Region)
TXNDC11
Reactivity: Human
WB, EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-TXNDC11 Antibody
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Target
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TXNDC11
(Thioredoxin Domain Containing 11 (TXNDC11))
Binding Specificity
All epitopes for TXNDC11 antibodies
AA 113-126, Internal Region
Reactivity
Human
Host
All hosts for TXNDC11 antibodies
Goat
Clonality
All clonalities for TXNDC11 antibodies
Polyclonal
Conjugate
All conjugates for TXNDC11 antibodies
This TXNDC11 antibody is un-conjugated
Application
All applications for TXNDC11 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Sequence
C-QLDYAEYVRR DSE
Specificity
Recognizes TXNDC11 (113-126).
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Immunogen
Peptide with sequence from the internal region of the protein sequence according to NP_056998.4. Genename: TXNDC11
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for TXNDC11
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Target
TXNDC11
(Thioredoxin Domain Containing 11 (TXNDC11))
Alternative Name
TXNDC11 (TXNDC11 Products )
Synonyms
EFP1 antibody, 2810408E11Rik antibody, AI427833 antibody, Txdc11 antibody, RGD1307538 antibody, thioredoxin domain containing 11 antibody, TXNDC11 antibody, Txndc11 antibody
Background
TXNDC11 May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation. Belongs to the protein disulfide isomerase family. Interacts with the cytoplasmic part of DUOX1 and DUOX2. Interacts with TPO and CYBA. 3 isoforms of the human protein are produced by alternative splicing.Synonyms: EF-hand-binding protein 1, EFP1, Thioredoxin domain-containing protein 11
Gene ID
51061
NCBI Accession
NP_056998
Pathways
Cell RedoxHomeostasis
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