ARID4A antibody (C-Term)

Catalog No. ABIN1105440

Product Details anti-ARID4A Antibody

Target: ARID4A (AT Rich Interactive Domain 4A (RBP1-Like) (ARID4A))

Binding Specificity: C-Term

Reactivity: Human, Dog, Cow, Mouse, Rat, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARID4A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NSSKCTPVKH LNVSKPQKLA RSPARISPHI KDGEKDKHRE KHPNSSPRTY

Cross-Reactivity (Details): Species reactivity (expected):Dog, Mouse, Rat, Bovine, ChickenSpecies reactivity (tested):Human

Purification: Purified using Protein A affinity column

Immunogen: The immunogen for anti-ARID4A antibody: synthetic peptide directed towards the C terminal of human ARID4A.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for ARID4A

Target: ARID4A (AT Rich Interactive Domain 4A (RBP1-Like) (ARID4A))

Alternative Name: ARID4A (ARID4A Products)

Synonyms: wu:fc43f03 antibody, wu:fi06c05 antibody, wu:fi11g07 antibody, wu:fi14h03 antibody, zgc:110391 antibody, ARID4A antibody, rbp1 antibody, rbbp1 antibody, rbp-1 antibody, MGC130902 antibody, RBBP-1 antibody, RBBP1 antibody, RBP-1 antibody, RBP1 antibody, A630009N03 antibody, A630067N03Rik antibody, MmRBBP1 antibody, Rbbp1 antibody, AT rich interactive domain 4A (RBP1-like) antibody, AT-rich interaction domain 4A antibody, AT-rich interaction domain 4A L homeolog antibody, arid4a antibody, ARID4A antibody, arid4a.L antibody, Arid4a antibody

Background: ARID4A encodes a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.Synonyms: ARID domain-containing protein 4A, AT-rich interactive domain-containing protein 4A, RBBP-1, RBBP1, RBP1, Retinoblastoma-binding protein 1

Gene ID: 5926

NCBI Accession: NP_002883