COL8a2 antibody (C-Term, Chain alpha 2)

Catalog No. ABIN951626

Product Details anti-COL8a2 Antibody

Target: COL8a2 (COL8A2) (Collagen, Type VIII, alpha 2 (COL8A2))

Binding Specificity: AA 578-607, C-Term, Chain alpha 2

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL8a2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human COL8A2. Other species not tested.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 578-607 amino acids from the C-terminal region of human COL8A2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for COL8a2

Target: COL8a2 (COL8A2) (Collagen, Type VIII, alpha 2 (COL8A2))

Abstract: COL8A2 Products

Synonyms: FECD antibody, FECD1 antibody, PPCD antibody, PPCD2 antibody, AI429819 antibody, collagen type VIII alpha 2 chain antibody, collagen, type VIII, alpha 2 antibody, COL8A2 antibody, Col8a2 antibody

Background: This gene encodes the alpha 2 chain of type VIII collagen. The protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2.Synonyms: COL8A2, Endothelial collagen

Molecular Weight: 67244 Da

Gene ID: 1296

NCBI Accession: NP_005193