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LEF1 antibody (N-Term)
LEF1
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-LEF1 Antibody
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Target
See all LEF1 Antibodies
LEF1
(Lymphoid Enhancer-Binding Factor 1 (LEF1))
Binding Specificity
All epitopes for LEF1 antibodies
AA 17-45, N-Term
Reactivity
All reactivities for LEF1 antibodies
Human
Host
All hosts for LEF1 antibodies
Rabbit
Clonality
All clonalities for LEF1 antibodies
Polyclonal
Conjugate
All conjugates for LEF1 antibodies
This LEF1 antibody is un-conjugated
Application
All applications for LEF1 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human LEF1 (N-term).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human LEF1
Isotype
Ig Fraction
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Discover our top product LEF1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for LEF1
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Target
LEF1
(Lymphoid Enhancer-Binding Factor 1 (LEF1))
Alternative Name
LEF1 (LEF1 Products )
Synonyms
LEF1 antibody, 3000002B05 antibody, AI451430 antibody, Lef-1 antibody, LEF-1 antibody, TCF10 antibody, TCF1ALPHA antibody, TCF7L3 antibody, lymphoid enhancer binding factor 1 antibody, lymphoid enhancer-binding factor 1 antibody, lymphoid enhancer factor XLEF-1B antibody, LEF1 antibody, lef1 antibody, Lef1 antibody
Background
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.Synonyms: LEF-1, Lymphoid enhancer-binding factor 1, T cell-specific transcription factor 1-alpha, TCF1-alpha
Molecular Weight
44201 Da
Gene ID
51176
NCBI Accession
NP_001124185
Pathways
WNT Signaling , Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Hormone Metabolic Process , Nuclear Hormone Receptor Binding , Chromatin Binding
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