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BIRC6 antibody (C-Term)

BIRC6 Reactivity: Human IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1450019
  • Target See all BIRC6 Antibodies
    BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))
    Binding Specificity
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 24
    • 3
    • 1
    Human
    Host
    • 21
    • 2
    • 1
    Rabbit
    Clonality
    • 23
    • 1
    Polyclonal
    Conjugate
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BIRC6 antibody is un-conjugated
    Application
    • 12
    • 12
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    A 17 amino acid synthetic peptide near the carboxy terminus of Human BIRC6
    Isotype
    IgG
    Top Product
    Discover our top product BIRC6 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))
    Alternative Name
    BIRC6 (BIRC6 Products)
    Synonyms
    APOLLON antibody, BRUCE antibody, bruce antibody, apollon antibody, BIRC6 antibody, A430032G04Rik antibody, A430040A19Rik antibody, AA501170 antibody, Bruce antibody, D630005A10Rik antibody, mKIAA1289 antibody, baculoviral IAP repeat containing 6 antibody, baculoviral IAP repeat-containing 6 antibody, BIRC6 antibody, Birc6 antibody, birc6 antibody
    Background
    Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. BRUCE, also known as BIRC6, is an IAP family member protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. BRUCE regulates p53 and the mitochondrial pathway of apoptosis by facilitating the degradation of apoptotic proteins such as Caspase-9 and SMAC by ubiquitination.Synonyms: Apollon, Baculoviral IAP repeat-containing protein 6, KIAA1289, Ubiquitin-conjugating BIR domain enzyme apollon
    Molecular Weight
    534 kDa
    Gene ID
    57448
    NCBI Accession
    NP_057336
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