CHD7 antibody (N-Term)

Catalog No. ABIN1450043

Product Details anti-CHD7 Antibody

Target: CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity chromatography purified via peptide column

Immunogen: CHD7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CHD7

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CHD7

Target: CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))

Alternative Name: CHD7 (CHD7 Products)

Synonyms: CHD7 antibody, fd19h06 antibody, si:ch211-197o6.2 antibody, wu:cegs2051 antibody, wu:fb37f10 antibody, wu:fb39h04 antibody, wu:fd19h06 antibody, HH5 antibody, IS3 antibody, KAL5 antibody, A730019I05Rik antibody, Cycn antibody, Cyn antibody, Dz antibody, Edy antibody, Flo antibody, GENA 47 antibody, GENA 60 antibody, Gena 52 antibody, Lda antibody, Mt antibody, Obt antibody, Todo antibody, WBE1 antibody, Whi antibody, metis antibody, chromodomain helicase DNA binding protein 7 L homeolog antibody, chromodomain helicase DNA binding protein 7 antibody, chd7.L antibody, CHD7 antibody, chd7 antibody, Chd7 antibody

Background: CHD proteins belong to a superfamily of proteins of ATP-dependent chromatin remodeling enzymes that have a unique combination of functional domains, including two N-terminal chromodomains, a SNF2-like ATPase/helicase domain and a DNA-binding domain. These proteins are thought to play a role in early embryonic development by affecting chromatin structure and gene expression. Mutations in one member of this family, CHD7, result in CHARGE syndrome. It colocalizes with embryonic stem (ES) cell master regulators OCT4/POU5F1, SOX2, and NANOG and is thought to modulate ES-specific gene transcription. Together with SOX2, CHD7 has been suggested to also regulate several human disease genes.Synonyms: ATP-dependent helicase CHD7, CHD-7, Chromodomain-helicase-DNA-binding protein 7, KIAA1416

Gene ID: 55636

UniProt: Q9P2D1

Pathways: Sensory Perception of Sound, Chromatin Binding