RNASET2 antibody (C-Term)

Catalog No. ABIN1450169

Product Details anti-RNASET2 Antibody

Target: RNASET2 (Ribonuclease T2 (RNASET2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASET2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid synthetic peptide near the carboxy terminus of Human RNASET2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RNASET2

Target: RNASET2 (Ribonuclease T2 (RNASET2))

Alternative Name: RNASET2 (RNASET2 Products)

Synonyms: RNASE6PL antibody, bA514O12.3 antibody, MGC83874 antibody, MGC145364 antibody, dre2 antibody, wu:fc10c06 antibody, zgc:113369 antibody, ribonuclease T2 antibody, ribonuclease T2 L homeolog antibody, ribonuclease t2 antibody, RNASET2 antibody, Rnaset2 antibody, rnaset2.L antibody, rnaset2 antibody, TM1040_2631 antibody, RPE_1409 antibody, Bind_1696 antibody, Dd586_2225 antibody, Nhal_0810 antibody, Snov_2442 antibody, Fbal_2689 antibody, Nitsa_0808 antibody, Mesop_3495 antibody

Background: RNASET2 is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement, and has been suggested to function as a tumor suppressor protein. Its expression is suppressed in Human T-cell Leukemia Virus type 1 (HTLV-1) infected cells following the binding of the HTLV-1 Tax protein to the RNASET2 promoter. As Adult T-cell leukemia (ATL) is one of the primary diseases caused by HTLV-1 infection, a reduction in the level of RNASET2 by Tax may play a role in ATL development.Synonyms: RNASE6PL, Ribonuclease 6, Ribonuclease T2

Gene ID: 8635

NCBI Accession: NP_003721