ITCH antibody (pTyr420)

Catalog No. ABIN5581097

Product Details anti-ITCH Antibody

Target: ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))

Binding Specificity: pTyr420

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITCH antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human ITCH.

Specificity: This antibody detects endogenous levels of ITCH only when phosphorylated at tyrosine 420.

Cross-Reactivity: Human, Mouse

Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y420 of human ITCH.

Application Details

Application Notes: Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS, pH 7.4 (without Mg²⁺ and Ca²⁺), (50 % glycerol, 0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
Avoid repeated freezing and thawing.

Target Details for ITCH

Target: ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))

Alternative Name: ITCH (ITCH Products)

Synonyms: AIF4 antibody, AIP4 antibody, NAPP1 antibody, dJ468O1.1 antibody, 6720481N21Rik antibody, 8030492O04Rik antibody, A130065M08 antibody, C230047C07Rik antibody, itchy E3 ubiquitin protein ligase antibody, itchy, E3 ubiquitin protein ligase antibody, ITCH antibody, Itch antibody

Background: Full Gene Name: itchy E3 ubiquitin protein ligase homolog (mouse)
Synonyms: AIF4,AIP4,NAPP1,dJ468O1.1

Gene ID: 83737

Pathways: Activation of Innate immune Response, CXCR4-mediated Signaling Events