PML antibody

Catalog No. ABIN5585866

Product Details anti-PML Antibody

Target: PML (Promyelocytic Leukemia (PML))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PML antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Purpose: Rabbit polyclonal antibody raised against partial recombinant PML.

Specificity: This antibody recognizes normal PML proteins of lower molecular weight, and also recognizes the high molecular weight PML/RARalpha chimeric protein in promyelocytic leukemia patients.

Cross-Reactivity: Human

Immunogen: Recombinant protein corresponding to the ring finger in the homodimerization region of human PML.

Application Details

Application Notes: Western Blot (1:5000)
Immunofluorescence (1:500)
Immunohistochemistry (1:100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from 10 mM PBS, pH 7.4

Storage: -20 °C

Storage Comment: Store at -20°C on dry atmosphere.
After reconstitution with appropriate volume of deionized water to reach a final antibody concentration of 1 mg/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.

Target Details for PML

Target: PML (Promyelocytic Leukemia (PML))

Alternative Name: PML (PML Products)

Synonyms: MYL antibody, PP8675 antibody, RNF71 antibody, TRIM19 antibody, 1200009E24Rik antibody, AI661194 antibody, Trim19 antibody, RGD1562602 antibody, PML antibody, promyelocytic leukemia antibody, PML antibody, Pml antibody

Background: Full Gene Name: promyelocytic leukemia
Synonyms: MYL,PP8675,RNF71,TRIM19

Gene ID: 5371

Pathways: p53 Signaling, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus