CYP2J2 antibody (AA 408-498)

Catalog No. ABIN560550

Product Details anti-CYP2J2 Antibody

Target: CYP2J2 (Cytochrome P450, Family 2, Subfamily J, Polypeptide 2 (CYP2J2))

Binding Specificity: AA 408-498

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CYP2J2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a partial recombinant CYP2J2.

Sequence: LHRDPTEWAT PDTFNPDHFL ENGQFKKREA FMPFSIGKRA CLGEQLARTE LFIFFTSLMQ KFTFRPPNNE KLSLKFRMGI TISPVSHRLC A

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CYP2J2 (NP_000766, 408 a.a. ~ 498 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2D10

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CYP2J2 antibody (ABIN560550)

Kaspera, Kirby, Sahele, Collier, Kharasch, Unadkat, Totah: "Investigating the contribution of CYP2J2 to ritonavir metabolism in vitro and in vivo." in: Biochemical pharmacology, Vol. 91, Issue 1, pp. 109-18, (2014) (PubMed).

Lee, Jones, Katayama, Kaspera, Jiang, Freiwald, Smith, Walker, Totah: "Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 5, pp. 943-51, (2012) (PubMed).

Herse, Lamarca, Hubel, Kaartokallio, Lokki, Ekholm, Laivuori, Gauster, Huppertz, Sugulle, Ryan, Novotny, Brewer, Park, Kacik, Hoyer, Verlohren, Wallukat, Rothe, Luft, Muller, Schunck, Staff, Dechend: "Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia." in: Circulation, Vol. 126, Issue 25, pp. 2990-9, (2012) (PubMed).

Pearson, Warren, Barrett, Khan: "Detection of EETs and HETE-generating cytochrome P-450 enzymes and the effects of their metabolites on myometrial and vascular function." in: American journal of physiology. Endocrinology and metabolism, Vol. 297, Issue 3, pp. E647-56, (2009) (PubMed).

Target Details for CYP2J2

Target: CYP2J2 (Cytochrome P450, Family 2, Subfamily J, Polypeptide 2 (CYP2J2))

Alternative Name: CYP2J2 (CYP2J2 Products)

Synonyms: CPJ2 antibody, CYP2J2 antibody, cytochrome P450 family 2 subfamily J member 2 antibody, cytochrome P450, family 2, subfamily J, polypeptide 20 antibody, cytochrome P450 family 2 subfamily J member 2 L homeolog antibody, cytochrome P450, family 2, subfamily J, polypeptide 2 antibody, CYP2J2 antibody, CYP2J20 antibody, cyp2j2.L antibody

Background: Full Gene Name: cytochrome P450, family 2, subfamily J, polypeptide 2
Synonyms: CPJ2

Gene ID: 1573

NCBI Accession: NM_000775