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eIF4EBP1 antibody (pSer65)

EIF4EBP1 Reactivity: Human WB, IHC, ELISA, FACS, ICC, Neut Host: Mouse Monoclonal 2D1G11 unconjugated
Catalog No. ABIN5611115
  • Target See all eIF4EBP1 (EIF4EBP1) Antibodies
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    Binding Specificity
    • 29
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    • 9
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    • 2
    • 2
    • 1
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    • 1
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    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
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    • 1
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    • 1
    pSer65
    Reactivity
    • 237
    • 165
    • 121
    • 21
    • 14
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
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    • 1
    Human
    Host
    • 256
    • 13
    • 4
    Mouse
    Clonality
    • 237
    • 38
    Monoclonal
    Conjugate
    • 116
    • 25
    • 18
    • 11
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    • 10
    • 10
    • 9
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    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This eIF4EBP1 antibody is un-conjugated
    Application
    • 217
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
    Immunogen
    Synthesized peptide of human Phospho-4E-BP1 (Ser65).
    Clone
    2D1G11
    Isotype
    IgG1
    Top Product
    Discover our top product EIF4EBP1 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: N/A, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    Alternative Name
    4E-BP1 (EIF4EBP1 Products)
    Synonyms
    4E-BP1 antibody, 4EBP1 antibody, BP-1 antibody, PHAS-I antibody, 4e-bp1 antibody, AA959816 antibody, 153432_at antibody, 43-BP antibody, 4E-BP antibody, 4EBP antibody, 4e-bp antibody, 4eBP antibody, 4ebp antibody, BcDNA.HL08053 antibody, BcDNA:HL08053 antibody, CG8846 antibody, CT8705 antibody, Dm 4E-BP antibody, Dmel\\CG8846 antibody, Phas1 antibody, Thor/EIF4EBP antibody, anon-WO0172774.158 antibody, d4E-BP antibody, d4E-BP1 antibody, d4EBP antibody, d4e-bp antibody, d4eBP antibody, dthor antibody, eIF4E-BP antibody, l(2)06270 antibody, l(2)k07736 antibody, l(2)k13517 antibody, pp20 antibody, thor antibody, EIF4EBP1 antibody, fc04h09 antibody, wu:fc04h09 antibody, zgc:64137 antibody, eukaryotic translation initiation factor 4E binding protein 1 antibody, CG8846 gene product from transcript CG8846-RA antibody, EIF4EBP1 antibody, Eif4ebp1 antibody, Thor antibody, eif4ebp1 antibody
    Background

    Description: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

    Aliases: EIF4EBP1, BP-1, 4EBP1, 4E-BP1, PHAS-I

    Molecular Weight
    12.6 kDa
    Gene ID
    1978
    HGNC
    1978
    Pathways
    MAPK Signaling, PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Cell Size, BCR Signaling
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