TNFRSF4 antibody (AA 29-214)
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- Target See all TNFRSF4 Antibodies
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
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Binding Specificity
- AA 29-214
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TNFRSF4 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human CD134 (AA: extra 29-214) expressed in E. coli.
- Clone
- 3G5G7
- Isotype
- IgG1
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 59-205) antibody
TNFRSF4 Reactivity: Human, Chimpanzee FACS, ELISA, IHC, IF, Coat, ISt, StM Host: Mouse Monoclonal OX40-3108 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) antibody (PE)TNFRSF4 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal Ber-ACT35 PE
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) antibody (FITC)TNFRSF4 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal Ber-ACT35 FITC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) antibody (APC)TNFRSF4 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal Ber-ACT35 APC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-214) antibodyTNFRSF4 Reactivity: Human WB, FACS, ELISA, IHC, ICC, Neut Host: Mouse Monoclonal 2D1B8 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) antibodyTNFRSF4 Reactivity: Human, Non-Human Primate WB, FACS, ELISA, IP, IHC (fro), IHC (p) Host: Mouse Monoclonal Ber-ACT35 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 101-200) antibodyTNFRSF4 Reactivity: Human, Mouse, Rat WB, ELISA, IF (p), IHC (fro), IF (cc), IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-214) antibodyTNFRSF4 Reactivity: Human WB, FACS, ELISA, IHC, ICC, Neut Host: Mouse Monoclonal 7B5E10 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-216) antibodyTNFRSF4 Reactivity: Human FACS, ELISA Host: Rabbit Monoclonal DM116 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 100-200) antibodyTNFRSF4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
- Alternative Name
- CD134 (TNFRSF4 Products)
- Synonyms
- TNFRSF4 antibody, ACT35 antibody, CD134 antibody, Ly-70 antibody, Ox40 antibody, TXGP1L antibody, Txgp1 antibody, OX40 antibody, TNF receptor superfamily member 4 antibody, tumor necrosis factor receptor superfamily, member 4 antibody, TNFRSF4 antibody, Tnfrsf4 antibody
- Background
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Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Aliases: TNFRSF4, OX40, ACT35, IMD16, TXGP1L
- Molecular Weight
- 29.3 kDa
- Gene ID
- 7293
- HGNC
- 7293
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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