NMDAR2A antibody (AA 23-165)

Catalog No. ABIN5611284

Product Details anti-NMDAR2A Antibody

Target: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Binding Specificity: AA 23-165

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NMDAR2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human GRIN2A (AA: extra 23-165) expressed in E. coli.

Clone: 3G10F9

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for NMDAR2A

Target: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Alternative Name: GRIN2A (GRIN2A Products)

Synonyms: NMDAR2A antibody, nr2a antibody, GRIN2A antibody, EPND antibody, GluN2A antibody, NR2A antibody, glutamate ionotropic receptor NMDA type subunit 2A antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog antibody, glutamate receptor ionotropic, NMDA 2A antibody, glutamate receptor, ionotropic, NMDA2A (epsilon 1) antibody, GRIN2A antibody, grin2a.L antibody, LOC100438553 antibody, Grin2a antibody

Background:

Description: This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.

Aliases: LKS, EPND, FESD, NR2A, GluN2A, NMDAR2A

Molecular Weight: 165.3 kDa

Gene ID: 2903

HGNC: 2903

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity