TFAP2B antibody (AA 84-193)
Quick Overview for TFAP2B antibody (AA 84-193) (ABIN5611289)
Target
See all TFAP2B AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 84-193
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Purpose
- TFAP2B Antibody
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Purification
- Purified antibody
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Immunogen
- Purified recombinant fragment of human TFAP2B (AA: 84-193) expressed in E. Coli.
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Isotype
- IgG2b
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Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TFAP2B (Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B))
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Alternative Name
- TFAP2B
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Background
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This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
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Molecular Weight
- 50.5 kDa
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UniProt
- Q92481
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Pathways
- Carbohydrate Homeostasis, Synaptic Membrane
Target
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