CD1c antibody (AA 18-302)

Catalog No. ABIN5611308

Product Details anti-CD1c Antibody

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Binding Specificity: AA 18-302

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD1c antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human CD1C (AA: extra 18-302) expressed in E. coli.

Clone: 2A7C11

Isotype: IgG2b

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for CD1c

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Alternative Name: CD1C (CD1C Products)

Background:

Description: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

Aliases: R7, CD1, CD1A, BDCA1

Molecular Weight: 37.7 kDa

Gene ID: 911

HGNC: 911