CD3G antibody (AA 23-116)

Catalog No. ABIN5611367

Product Details anti-CD3G Antibody

Target: CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))

Binding Specificity: AA 23-116

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3G antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human CD3G (AA: extra 23-116) expressed in E. coli.

Clone: 5B7F9

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for CD3G

Target: CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))

Alternative Name: CD3G (CD3G Products)

Synonyms: Ctg-3 antibody, Ctg3 antibody, T3g antibody, CD3-GAMMA antibody, T3G antibody, CD3 antigen, gamma polypeptide antibody, CD3g molecule antibody, Cd3g antibody, CD3G antibody

Background:

Description: The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.

Aliases: T3G, IMD17, CD3-GAMMA

Molecular Weight: 20.5 kDa

Gene ID: 917

HGNC: 917

Pathways: TCR Signaling, CXCR4-mediated Signaling Events