HMGCL antibody (AA 1-325)

Catalog No. ABIN561291

Product Details anti-HMGCL Antibody

Target: HMGCL (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))

Binding Specificity: AA 1-325

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HMGCL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a full length recombinant HMGCL.

Sequence: MAAMRKALPR RLVGLASLRA VSTSSMGTLP KRVKIVEVGP RDGLQNEKNI VSTPVKIKLI DMLSEAGLSV IETTSFVSPK WVPQMGDHTE VLKGIQKFPG INYPVLTPNL KGFEAAVAAG AKEVVIFGAA SELFTKKNIN CSIEESFQRF DAILKAAQSA NISVRGYVSC ALGCPYEGKI SPAKVAEVTK KFYSMGCYEI SLGDTIGVGT PGIMKDMLSA VMQEVPLAAL AVHCHDTYGQ ALANTLMALQ MGVSVVDSSV AGLGGCPYAQ GASGNLATED LVYMLEGLGI HTGVNLQKLL EAGNFICQAL NRKTSSKVAQ ATCKL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: HMGCL (AAH10570, 1 a.a. ~ 325 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 4F4-D1

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-HMGCL antibody (ABIN561291)

Arnedo, Menao, Puisac, Teresa-Rodrigo, Gil-Rodríguez, López-Viñas, Gómez-Puertas, Casals, Casale, Hegardt, Pié: "Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol." in: Journal of lipid research, Vol. 53, Issue 10, pp. 2046-56, (2012) (PubMed).

Puisac, Arnedo, Casale, Ribate, Castiella, Ramos, Ribes, Pérez-Cerdá, Casals, Hegardt, Pié: "Differential HMG-CoA lyase expression in human tissues provides clues about 3-hydroxy-3-methylglutaric aciduria." in: Journal of inherited metabolic disease, Vol. 33, Issue 4, pp. 405-10, (2010) (PubMed).

Target Details for HMGCL

Target: HMGCL (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))

Alternative Name: HMGCL (HMGCL Products)

Synonyms: Afu7g01720 antibody, AO090038000541 antibody, AW476067 antibody, HL antibody, zgc:56248 antibody, 3-hydroxymethyl-3-methylglutaryl-CoA lyase S homeolog antibody, 3-hydroxymethyl-3-methylglutaryl-CoA lyase antibody, 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase antibody, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase antibody, hmgcl.S antibody, HMGCL antibody, AFUA_7G01720 antibody, NFIA_114450 antibody, ACLA_065820 antibody, AOR_1_910074 antibody, PMAA_004600 antibody, TSTA_103060 antibody, ARB_04874 antibody, TRV_06573 antibody, Hmgcl antibody, hmgcl antibody

Background: Full Gene Name: 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase
Synonyms: HL

Gene ID: 3155