KCNJ10 antibody (AA 276-379)

Catalog No. ABIN561584

There is 1 publication for this product available. The Mouse Monoclonal anti-KCNJ10 antibody is suitable to detect KCNJ10 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for KCNJ10 antibody (AA 276-379) (ABIN561584)

Target: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KCNJ10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1C11

Product Details anti-KCNJ10 Antibody

Binding Specificity: AA 276-379

Purpose: Mouse monoclonal antibody raised against a partial recombinant KCNJ10.

Sequence: DFELVLILSG TVESTSATCQ VRTSYLPEEI LWGYEFTPAI SLSASGKYIA DFSLFDQVVK VASPSGLRDS TVRYGDPEKL KLEESLREQA EKEGSALSVR ISNV

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: KCNJ10 (NP_002232, 276 a.a. ~ 379 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-KCNJ10 antibody (ABIN561584)

Singh, Wangemann: "Free radical stress-mediated loss of Kcnj10 protein expression in stria vascularis contributes to deafness in Pendred syndrome mouse model." in: American journal of physiology. Renal physiology, Vol. 294, Issue 1, pp. F139-48, (2008) (PubMed).

Target Details for KCNJ10

Target: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Alternative Name: KCNJ10

Background: Full Gene Name: potassium inwardly-rectifying channel, subfamily J, member 10
Synonyms: BIRK-10,KCNJ13-PEN,KIR1.2,KIR4.1

Gene ID: 3766

NCBI Accession: NM_002241

Pathways: Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity