PSMB8 antibody (AA 173-272)

Catalog No. ABIN562483

This Mouse Monoclonal antibody specifically detects PSMB8 in WB, ELISA, IP, IF and IHC (p). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for PSMB8 antibody (AA 173-272) (ABIN562483)

Target: PSMB8 (Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PSMB8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1B3

Product Details anti-PSMB8 Antibody

Binding Specificity: AA 173-272

Purpose: Mouse monoclonal antibody raised against a partial recombinant PSMB8.

Sequence: DKKGPGLYYV DEHGTRLSGN MFSTGSGNTY AYGVMDSGYR PNLSPEEAYD LGRRAIAYAT HRDSYSGGVV NMYHMKEDGW VKVESTDVSD LLHQYREANQ

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PSMB8 (AAH01114, 173 a.a. ~ 272 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PSMB8 antibody (ABIN562483)

Nijholt, de Graaf, van Haastert, Oliveira, Berkers, Zwart, Ovaa, Baas, Hoozemans, Scheper: "Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: implications for Alzheimer's disease." in: Cell death and differentiation, Vol. 18, Issue 6, pp. 1071-81, (2011) (PubMed).

Target Details for PSMB8

Target: PSMB8 (Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))

Alternative Name: PSMB8

Background: Full Gene Name: proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
Synonyms: D6S216,D6S216E,LMP7,MGC1491,PSMB5i,RING10,beta5i

Gene ID: 5696

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA