F13A1 antibody (AA 46-181)

Catalog No. ABIN5646874

Product Details anti-F13A1 Antibody

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Binding Specificity: AA 46-181

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This F13A1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Purified

Purity: Protein G affinity chromatography

Immunogen: A human partial recombinant protein corresponding to amino acids 46-181 was used as the immunogen for the Factor XIIIa antibody.

Clone: F13A1-1448

Isotype: IgG2b kappa

Application Details

Application Notes: Titering of the Factor XIIIa antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Prediluted IHC only format: incubate for 30 min at RT

Restrictions: For Research Use only

Handling

Buffer: Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, *For IHC use only*

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Factor XIIIa antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for F13A1

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Alternative Name: Factor XIIIa / F13A1 (F13A1 Products)

Synonyms: F13a antibody, f13a1 antibody, wu:fo83d04 antibody, zgc:153334 antibody, F13A1 antibody, F13A antibody, 1200014I03Rik antibody, AI462306 antibody, coagulation factor XIII A1 chain antibody, coagulation factor XIII, A1 polypeptide b antibody, coagulation factor XIII A chain antibody, coagulation factor XIII, A1 subunit antibody, F13a1 antibody, f13a1b antibody, F13A1 antibody

Background: Factor XIIIa has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-Factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans (-/+) and desmoplastic malignant melanoma (-). Anti-Factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma.