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S100B antibody

S100B Reactivity: Human, Rat, Mouse, Cow IHC (p) Host: Mouse Monoclonal S100B-1012 unconjugated
Catalog No. ABIN5646939
  • Target See all S100B Antibodies
    S100B (S100 Calcium Binding Protein B (S100B))
    Reactivity
    • 157
    • 93
    • 62
    • 44
    • 18
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Cow
    Host
    • 127
    • 66
    • 7
    • 2
    • 2
    • 1
    Mouse
    Clonality
    • 114
    • 91
    Monoclonal
    Conjugate
    • 84
    • 31
    • 21
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This S100B antibody is un-conjugated
    Application
    • 140
    • 80
    • 64
    • 59
    • 48
    • 25
    • 25
    • 19
    • 18
    • 15
    • 13
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Purified
    Purity
    Protein G affinity chromatography
    Immunogen
    Recombinant full-length human protein was used as the immunogen for the S100 beta antibody.
    Clone
    S100B-1012
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product S100B Primary Antibody
  • Application Notes
    Optimal dilution of the S100 beta antibody should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Prediluted IHC only format: incubate for 30 min at RT

    Restrictions
    For Research Use only
  • Buffer
    Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, *For IHC use only*
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store the S100 beta antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target
    S100B (S100 Calcium Binding Protein B (S100B))
    Alternative Name
    S100B (S100B Products)
    Synonyms
    NEF antibody, S100 antibody, S100-B antibody, S100beta antibody, S100P antibody, AI850290 antibody, Bpb antibody, si:dkey-110p14.2 antibody, wu:fq18b10 antibody, zgc:92776 antibody, S100 calcium binding protein B antibody, S100 protein, beta polypeptide, neural antibody, S100 calcium binding protein, beta (neural) antibody, S100B antibody, S100b antibody, s100b antibody
    Background
    S100 belongs to the family of calcium binding proteins. S100 alpha and S100 beta proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S100A and S100B) but not on the alpha-chain of S100 (i.e. in S100A and S100A0). This antibody can be used to localize S100A and S100B in various tissue sections. S100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S100 protein.
    Pathways
    Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
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