ALDH1A3 antibody

Catalog No. ABIN5647014

Product Details anti-ALDH1A3 Antibody

Target: ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH1A3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogen: Amino acids N37-K154 from the human protein were used as the immunogen for the ALDH1A3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ALDH1A3 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the ALDH1A3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for ALDH1A3

Target: ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))

Alternative Name: ALDH1A3 (ALDH1A3 Products)

Synonyms: RALDH3 antibody, ALDH1A3 antibody, ALDH1A6 antibody, ALDH6 antibody, MCOP8 antibody, Aldh6 antibody, V1 antibody, aldehyde dehydrogenase 1 family member A3 antibody, aldehyde dehydrogenase 1 family member A3 L homeolog antibody, aldehyde dehydrogenase 1 family, member A3 antibody, aldehyde dehydrogenase family 1, subfamily A3 antibody, ALDH1A3 antibody, aldh1a3.L antibody, aldh1a3 antibody, Aldh1a3 antibody

Background: Aldehyde dehydrogenase 1 family, member A3, also known as ALDH1A3 or retinaldehyde dehydrogenase 3 (RALDH3), is an enzyme that in humans is encoded by the ALDH1A3 gene. Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by this gene uses retinal as a substrate, either in a free or a cellular retinol-binding protein form. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants.

UniProt: P47895

Pathways: Retinoic Acid Receptor Signaling Pathway