APOC3 antibody

Catalog No. ABIN5647021

Product Details anti-APOC3 Antibody

Target: APOC3 (Apolipoprotein C-III (APOC3))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOC3 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): Expected species reactivity: Human

Purification: Antigen affinity purified

Immunogen: Amino acids S21-A99 from the human protein were used as the immunogen for the APOC3 antibody.

Isotype: IgG

Application Details

Application Notes: Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the APOC3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for APOC3

Target: APOC3 (Apolipoprotein C-III (APOC3))

Alternative Name: APOC3 / Apolipoprotein C III (APOC3 Products)

Synonyms: APOC3 antibody, APOCIII antibody, HALP2 antibody, Apoc antibody, ApoC-III antibody, apo-CIII antibody, Apo-CIII antibody, apolipoprotein C3 antibody, apolipoprotein C-III antibody, APOC3 antibody, Apoc3 antibody

Background: Apolipoprotein C-III, also known as apo-CIII, is a protein that in humans is encoded by the APOC3 gene. Apo-CIII is a component of very low density lipoprotein (VLDL). APOC3 inhibits lipoprotein lipase and hepatic lipase, it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.

UniProt: P02656

Pathways: Carbohydrate Homeostasis, Lipid Metabolism