BANP antibody (AA 30-390)

Catalog No. ABIN5647046

Product Details anti-BANP Antibody

Target: BANP (Protein BANP (BANP))

Binding Specificity: AA 30-390

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BANP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Purified

Immunogen: A human recombinant protein of amino acids 30-390 was used as the immunogen for the BANP antibody.

Clone: 1524CT337-6-32

Isotype: IgG1 kappa

Application Details

Application Notes: Western blot: 1:500-1000,IHC (FFPE): 1:25

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the BANP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for BANP

Target: BANP (Protein BANP (BANP))

Alternative Name: BANP (BANP Products)

Synonyms: smar1 antibody, smarbp1 antibody, MGC76079 antibody, MGC89601 antibody, BEND1 antibody, SMAR1 antibody, SMARBP1 antibody, AA408158 antibody, zgc:111954 antibody, BTG3 associated nuclear protein antibody, Btg3 associated nuclear protein antibody, BTG3 associated nuclear protein L homeolog antibody, banp antibody, BANP antibody, Banp antibody, banp.L antibody

Background: Btg3-associated nuclear protein controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).

Gene ID: 54971

UniProt: Q8N9N5