ABCD1 antibody (AA 257-285)

Catalog No. ABIN5647318

Product Details anti-ABCD1 Antibody

Target: ABCD1 (ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))

Binding Specificity: AA 257-285

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 257-285 from the human protein was used as the immunogen for this ABCD1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ABCD1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ABCD1

Target: ABCD1 (ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))

Alternative Name: ABCD1 (ABCD1 Products)

Synonyms: ABC42 antibody, ALD antibody, ALDP antibody, AMN antibody, RGD1562128 antibody, zgc:172102 antibody, ABCD1 antibody, Ald antibody, Aldgh antibody, ATP binding cassette subfamily D member 1 antibody, ATP-binding cassette, sub-family D (ALD), member 1 antibody, ATP-binding cassette sub-family D member 1 antibody, ATP binding cassette subfamily D member 1 L homeolog antibody, ABCD1 antibody, Abcd1 antibody, abcd1 antibody, CpipJ_CPIJ013253 antibody, VDBG_05717 antibody, abcd1.L antibody

Background: ABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

UniProt: P33897

Pathways: Monocarboxylic Acid Catabolic Process