XDH antibody

Catalog No. ABIN5647630

Product Details anti-XDH Antibody

Target: XDH (Xanthine Dehydrogenase (XDH))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XDH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity (Details): Expected species reactivity: Human

Purification: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids T2-K343 was used as the immunogen for the Xanthine Oxidase antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Xanthine Oxidase antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Xanthine Oxidase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for XDH

Target: XDH (Xanthine Dehydrogenase (XDH))

Alternative Name: Xanthine Oxidase (XDH Products)

Synonyms: XO antibody, XOR antibody, Xor antibody, Xox-1 antibody, Xox1 antibody, XDH antibody, im:7146167 antibody, DDBDRAFT_0219626 antibody, DDBDRAFT_0230176 antibody, DDB_0219626 antibody, DDB_0230176 antibody, xanthine dehydrogenase antibody, xanthine dehydrogenase/oxidase antibody, Xanthine dehydrogenase antibody, XDH antibody, Xdh antibody, xdh antibody, LOC576712 antibody, Trebr_1754 antibody

Background: Xanthine dehydrogenase, also known as XDH, is a protein that, in humans, is encoded by the XDH gene. Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.

UniProt: P47989

Pathways: Positive Regulation of Endopeptidase Activity