CA2 antibody

Catalog No. ABIN5647703

Product Details anti-CA2 Antibody

Target: CA2 (Carbonic Anhydrase II (CA2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: Antigen affinity purified

Immunogen: Amino acids S2-K260 from the human protein were used as the immunogen for the CA2 antibody.

Isotype: IgG

Application Details

Application Notes: Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,FACS: 1-3 μg/10^6 cells

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: Prior to reconstitution, store at 4°C. After reconstitution, the CA2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for CA2

Target: CA2 (Carbonic Anhydrase II (CA2))

Alternative Name: CA2 / Carbonic Anhydrase II (CA2 Products)

Synonyms: CG6906 antibody, CT21171 antibody, Dmel\\CG6906 antibody, CA-2 antibody, caII antibody, car2 antibody, ca ii antibody, ca-ii antibody, BETA CA2 antibody, BETA CARBONIC ANHYDRASE 2 antibody, CA18 antibody, CARBONIC ANHYDRASE 18 antibody, CARBONIC ANHYDRASE 2 antibody, T9L3.40 antibody, T9L3_40 antibody, carbonic anhydrase 2 antibody, LOC100135827 antibody, AI131712 antibody, CAII antibody, Ca2 antibody, Car-2 antibody, Ltw-5 antibody, Lvtw-5 antibody, CA-II antibody, CAC antibody, Car2 antibody, CAR3 antibody, Carbonic anhydrase 2 antibody, carbonic anhydrase 2 L homeolog antibody, carbonic anhydrase 2 antibody, carbonic anhydrase 1 antibody, carbonic anhydrase II antibody, carbonic anhydrase, alpha type, periplasmic antibody, CAH2 antibody, ca2.L antibody, ca2 antibody, CA2 antibody, HCAG_04637 antibody, LOC100135827 antibody, LOC100635510 antibody, Car2 antibody, Ca2 antibody, LOC100154873 antibody, LOC101113341 antibody

Background: CA2 is a cytosolic enzyme with the highest activity among all known CAs. The carbonic anhydrases (ACs) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs relatively slowly in the absence of a catalyst. Mutations in the CA2 gene result in the CA II deficiency syndrome, an autosomal recessive disorder that produces osteopetrosis, renal tubular acidosis and cerebral calcification. This gene is mapped to 8q22.

UniProt: P00918