LILRA3 antibody (AA 1-439)

Catalog No. ABIN564777

Product Details anti-LILRA3 Antibody

Target: LILRA3 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3))

Binding Specificity: AA 1-439

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LILRA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a full length recombinant LILRA3.

Sequence: MTSILTVLIC LGLSLDPRTH VQAGPLPKPT LWAEPGSVIT QGSPVTLRCQ GSLETQEYHL YREKKTALWI TRIPQELVKK GQFPILSITW EHAGRYCCIY GSHTVGLSES SDPLELVVTG AYSKPTLSAL PSPVVTSGGN VTIQCDSQVA FDGFILCKEG EDEHPQCLNS HSHARGSSRA IFSVGPVSPS RRWSYRCYGY DSRAPYVWSL PSDLLGLLVP GVSKKPSLSV QPGPVVAPGE KLTFQCGSDA GYDRFVLYKE WGRDFLQRPG RQPQAGLSQA NFTLGPVSRS YGGQYTCSGA YNLSSEWSAP SDPLDILITG QIRARPFLSV RPGPTVASGE NVTLLCQSQG GMHTFLLTKE GAADSPLRLK SKRQSHKYQA EFPMSPVTSA HAGTYRCYGS LSSNPYLLTH PSDPLELVVS GAAETLSPPQ NKSDSKAGE

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: LILRA3 (AAH28208.1, 1 a.a. ~ 439 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2E9

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-LILRA3 antibody (ABIN564777)

An, Brettle, Lee, Heng, Lim, Guillemin, Lord, Klotzsch, Geczy, Bryant, Fath, Tedla: "Soluble LILRA3 promotes neurite outgrowth and synapses formation through a high-affinity interaction with Nogo 66." in: Journal of cell science, Vol. 129, Issue 6, pp. 1198-209, (2016) (PubMed).

An, Lim, Guillemin, Vollmer-Conna, Rawlinson, Bryant, Tedla et al.: "Serum Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3) Is Increased in Patients with Multiple Sclerosis and Is a Strong Independent Indicator of Disease Severity; 6.7kbp LILRA3 Gene Deletion Is Not ..." in: PLoS ONE, Vol. 11, Issue 2, pp. e0149200, (2016) (PubMed).

Low, Ahrenstorf, Pommerenke, Habermann, Schughart, Ordóñez, Stripecke, Wilk, Witte: "TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads." in: Retrovirology, Vol. 13, pp. 15, (2016) (PubMed).

Lee, Mitchell, Liu Lau, An, Rajeaskariah, Wasinger, Raftery, Bryant, Tedla: "Glycosylation in a mammalian expression system is critical for the production of functionally active leukocyte immunoglobulin-like receptor A3 protein." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 32873-85, (2013) (PubMed).

An, Chandra, Piraino, Borges, Geczy, McNeil, Bryant, Tedla et al.: "Soluble LILRA3, a potential natural antiinflammatory protein, is increased in patients with rheumatoid arthritis and is tightly regulated by interleukin 10, tumor necrosis factor-alpha, and ..." in: The Journal of rheumatology, Vol. 37, Issue 8, pp. 1596-606, (2010) (PubMed).

Target Details for LILRA3

Target: LILRA3 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3))

Alternative Name: LILRA3 (LILRA3 Products)

Synonyms: CD85E antibody, HM31 antibody, HM43 antibody, ILT-6 antibody, ILT6 antibody, LIR-4 antibody, LIR4 antibody, e3 antibody, leukocyte immunoglobulin like receptor A3 antibody, LILRA3 antibody

Background: Full Gene Name: leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
Synonyms: CD85E,HM31,HM43,ILT6,LIR-4,LIR4,e3

Gene ID: 11026