CLPX antibody

Catalog No. ABIN5647975

Product Details anti-CLPX Antibody

Target: CLPX (ClpX Caseinolytic Peptidase X (CLPX))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLPX antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids A337-E574 was used as the immunogen for the CLPX antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CLPX antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the CLPX antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for CLPX

Target: CLPX (ClpX Caseinolytic Peptidase X (CLPX))

Alternative Name: CLPX / Caseinolytic protease X (CLPX Products)

Synonyms: AU014732 antibody, E330029I21 antibody, caseinolytic mitochondrial matrix peptidase chaperone subunit antibody, Clpx antibody, CLPX antibody

Background: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial is an enzyme that in humans is encoded by the CLPX gene. This protein is a member of the family of AAA Proteins (AAA+ ATPase) and is to form the protein complex of Clp protease. The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.

UniProt: O76031