TCF7L2 antibody (AA 400-500) (Atto 594)
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- Target See all TCF7L2 Antibodies
- TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
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Binding Specificity
- AA 400-500
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TCF7L2 antibody is conjugated to Atto 594
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- Detected in epithelium from small intestine, with the highest expression at the top of the crypts and a gradient of expression from crypt to villus. Detected in colon epithelium and colon cancer, and in epithelium from mammary gland and carcinomas derived therefrom.,Detects 68 kDa, band at ~55 kDa is another isoform, band at ~75 kDa is due to post translational modification.
- Cross-Reactivity
- Human, Rat
- Purification
- Peptide Affinity Purified
- Immunogen
- Synthetic peptide of Human TCF7L2 (400-500 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).
- Top Product
- Discover our top product TCF7L2 Primary Antibody
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- Application Notes
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- WB (1:1000)
- IHC (1:50)
- optimal dilutions for assays should be determined by the user.
- Comment
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A 1:1000 dilution of ABIN5651139 was sufficient for detection of TCF7L2 in 15 μg of rat kidney cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Conjugated antibodies should be stored at 4°C
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- Target
- TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
- Alternative Name
- TCF7L2 (TCF7L2 Products)
- Synonyms
- TCF4B antibody, TCF4E antibody, Tcf-4 antibody, Tcf4 antibody, mTcf-4B antibody, mTcf-4E antibody, tcf4 antibody, XTCF-4 antibody, tcf4e antibody, TCF4 antibody, TCF-4 antibody, TCFL2 antibody, transcription factor 7 like 2 antibody, transcription factor 7-like 2 antibody, transcription factor 7 like 2, T cell specific, HMG box antibody, transcription factor 7 like 2 L homeolog antibody, transcription factor 7-like 2 (T-cell specific, HMG-box) antibody, TCF7L2 antibody, LOC100545943 antibody, Tcf7l2 antibody, tcf7l2 antibody, tcf7l2.L antibody
- Gene ID
- 6934
- NCBI Accession
- NP_001139746
- UniProt
- Q9NQB0
- Pathways
- WNT Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus
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