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RRM2B antibody (AA 3-84)

RRM2B Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 6C1 unconjugated
Catalog No. ABIN565482
  • Target See all RRM2B Antibodies
    RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
    Binding Specificity
    • 15
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-84
    Reactivity
    • 39
    • 36
    • 21
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 52
    • 2
    Mouse
    Clonality
    • 52
    • 2
    Monoclonal
    Conjugate
    • 22
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RRM2B antibody is un-conjugated
    Application
    • 47
    • 23
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant RRM2B.
    Sequence
    DPERPEAAGL DQDERSSSDT NESEIKSNEE PLLRKSSRRF VIFPIQYPDI WKMYKQAQAS FWTAEEVDLS KDLPHWNKLK AD
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    RRM2B (NP_056528, 3 a.a. ~ 84 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    6C1
    Isotype
    IgG2b
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Park, Kim, Piao, Kang, Park, Kim, Lee: "p53R2 regulates thioredoxin reductase activity through interaction with TrxR2." in: Biochemical and biophysical research communications, Vol. 482, Issue 4, pp. 706-712, (2016) (PubMed).

    Piao, Jin, Kim, Lee, Amatya, Hyun, Chang, You: "Ribonucleotide reductase small subunit p53R2 suppresses MEK-ERK activity by binding to ERK kinase 2." in: Oncogene, Vol. 28, Issue 21, pp. 2173-84, (2009) (PubMed).

  • Target
    RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
    Alternative Name
    RRM2B (RRM2B Products)
    Synonyms
    p53r2 antibody, RRM2B antibody, MTDPS8A antibody, MTDPS8B antibody, P53R2 antibody, p53R2 antibody, ribonucleotide reductase M2 B (TP53 inducible) S homeolog antibody, ribonucleotide reductase regulatory TP53 inducible subunit M2B antibody, ribonucleotide reductase M2 B (TP53 inducible) antibody, rrm2b.S antibody, RRM2B antibody, rrm2b antibody, Rrm2b antibody
    Background
    Full Gene Name: ribonucleotide reductase M2 B (TP53 inducible)
    Synonyms: DKFZp686M05248,MGC102856,MGC42116,p53R2
    Gene ID
    50484
    NCBI Accession
    NM_015713
    Pathways
    p53 Signaling, Negative Regulation of intrinsic apoptotic Signaling
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