CYP26B1 antibody (AA 131-230)

Catalog No. ABIN566029

Product Details anti-CYP26B1 Antibody

Target: CYP26B1 (Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1))

Binding Specificity: AA 131-230

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CYP26B1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a partial recombinant CYP26B1.

Sequence: SNSIGDIHRN KRKVFSKIFS HEALESYLPK IQLVIQDTLR AWSSHPEAIN VYQEAQKLTF RMAIRVLLGF SIPEEDLGHL FEVYQQFVDN VFSLPVDLPF

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CYP26B1 (NP_063938, 131 a.a. ~ 230 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1H6

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CYP26B1 antibody (ABIN566029)

Chen, Lee, Hsu, Chen, Wang, Chen, Wang, Huang, Huang: "Expression of a splice variant of CYP26B1 in betel quid-related oral cancer." in: TheScientificWorldJournal, Vol. 2014, pp. 810561, (2014) (PubMed).

Elmabsout, Kumawat, Saenz-Méndez, Krivospitskaya, Sävenstrand, Olofsson, Eriksson, Strid, Valen, Törmä, Sirsjö: "Cloning and functional studies of a splice variant of CYP26B1 expressed in vascular cells." in: PLoS ONE, Vol. 7, Issue 5, pp. e36839, (2012) (PubMed).

Chen, Lee, Chen, Shieh, Ho, Wang, Lee, Yang, Chen, Chiang, Ko: "CYP26B1 is a novel candidate gene for betel quid-related oral squamous cell carcinoma." in: Oral oncology, Vol. 47, Issue 7, pp. 594-600, (2011) (PubMed).

Pavez Loriè, Li, Vahlquist, Törmä: "The involvement of cytochrome p450 (CYP) 26 in the retinoic acid metabolism of human epidermal keratinocytes." in: Biochimica et biophysica acta, Vol. 1791, Issue 3, pp. 220-8, (2009) (PubMed).

Target Details for CYP26B1

Target: CYP26B1 (Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1))

Alternative Name: CYP26B1 (CYP26B1 Products)

Background: Full Gene Name: cytochrome P450, family 26, subfamily B, polypeptide 1
Synonyms: CYP26A2,DKFZp686G0638,MGC129613,P450RAI-2

Gene ID: 56603

NCBI Accession: NM_019885

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Monocarboxylic Acid Catabolic Process