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CYP2B6 antibody (AA 160-340)

CYP2B6 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1679474
  • Target See all CYP2B6 Antibodies
    CYP2B6 (Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6))
    Binding Specificity
    • 15
    • 8
    • 7
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 160-340
    Reactivity
    • 49
    • 18
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 46
    • 2
    • 1
    Rabbit
    Clonality
    • 47
    • 2
    Polyclonal
    Conjugate
    • 21
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP2B6 antibody is un-conjugated
    Application
    • 43
    • 25
    • 20
    • 19
    • 13
    • 13
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    SKGALMDPTF LFQSITANII CSIVFGKRFH YQDQEFLKML NLFYQTFSLI SSVFGQLFEL FSGFLKYFPG AHRQVYKNLQ EINAYIGHSV EKHRETLDPS APKDLIDTYL LHMEKEKSNA HSEFSHQNLN LNTLSLFFAG TETTSTTLRY GFLLMLKYPH VAERVYREIE QVIGPHRPPE L
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 160-340 of human CYP2B6 (NP_000758.1).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:1000,IHC,1:50 - 1:100
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CYP2B6 (Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6))
    Alternative Name
    CYP2B6 (CYP2B6 Products)
    Synonyms
    CPB6 antibody, CYP2B antibody, CYP2B7 antibody, CYP2B7P antibody, CYPIIB6 antibody, EFVM antibody, IIB1 antibody, P450 antibody, CPF3 antibody, CYP4F antibody, LTB4H antibody, CYP2B30 antibody, CYP2B11 antibody, CYPIIB11 antibody, 21-OH antibody, 21OH antibody, 21OHA antibody, 21OHB antibody, CYP21OH-A antibody, Cyp21 antibody, Cyp21-ps1 antibody, Cyp21B antibody, Cyp21a2-ps antibody, Cyp21a2ps antibody, Oh21-1 antibody, Oh21-2 antibody, CYP2B6 antibody, cytochrome P450 family 2 subfamily B member 6 antibody, cytochrome P450 family 4 subfamily F member 3 antibody, cytochrome P450, family 2, subfamily B, polypeptide 6 antibody, cytochrome P450 family 2 subfamily B member 6 L homeolog antibody, cytochrome P450 2B11 antibody, cytochrome P450, family 21, subfamily a, polypeptide 1 antibody, cytochrome P450 subfamily 2B antibody, cytochrome P450 2B11-like antibody, CYP2B6 antibody, CYP4F3 antibody, cyp2b6.L antibody, Cyp21a1 antibody, LOC100068603 antibody
    Background
    This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described, however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.,CYP2B6,CPB6,CYP2B,CYP2B7,CYP2B7P,CYPIIB6,EFVM,IIB1,P450,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Lipid Metabolism,Cytochromes,Lipases,Drug metabolism,Cardiovascular,Lipids,CYP2B6
    Molecular Weight
    33 kDa/56 kDa
    Gene ID
    1555
    UniProt
    P20813
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