CLN3 antibody (AA 1-280)

Catalog No. ABIN1679284

Product Details anti-CLN3 Antibody

Target: CLN3 (Ceroid-Lipofuscinosis, Neuronal 3 (CLN3))

Binding Specificity: AA 1-280

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MGGCAGSRRR FSDSEGEETV PEPRLPLLDH QGAHWKNAVG FWLLGLCNNF SYVVMLSAAH DILSHKRTSG NQSHVDPGPT PIPHNSSSRF DCNSVSTAAV LLADILPTLV IKLLAPLGLH LLPYSPRVLV SGICAAGSFV LVAFSHSVGT SLCGVVFASI SSGLGEVTFL SLTAFYPRAV ISWWSSGTGG AGLLGALSYL GLTQAGLSPQ QTLLSMLGIP ALLLASYFLL LTSPEAQDPG GEEEAESAAR QPLIRTEAPE SKPGSSSSLS LRERWTVFKG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human CLN3 (NP_001035897.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CLN3

Target: CLN3 (Ceroid-Lipofuscinosis, Neuronal 3 (CLN3))

Alternative Name: CLN3 (CLN3 Products)

Synonyms: BTS antibody, JNCL antibody, AI323623 antibody, zgc:92244 antibody, GB12798 antibody, MGC80041 antibody, bts antibody, CLN3, battenin antibody, ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) antibody, ceroid-lipofuscinosis, neuronal 3 antibody, battenin antibody, ceroid-lipofuscinosis, neuronal 3 L homeolog antibody, uncharacterized LOC467935 antibody, CLN3 antibody, Cln3 antibody, cln3 antibody, PTRG_05620 antibody, LOC410860 antibody, cln3.L antibody, LOC467935 antibody

Background: This gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene.,CLN3,BTN1,BTS,JNCL,battenin,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Neurodegenerative Diseases,CLN3

Molecular Weight: 28 kDa/34 kDa/37 kDa/42 kDa/45 kDa/47 kDa

Gene ID: 1201

UniProt: Q13286