GABRA4 antibody (AA 36-258)

Catalog No. ABIN1679929

Product Details anti-GABRA4 Antibody

Target: GABRA4 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4))

Binding Specificity: AA 36-258

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRA4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QNQKEEKLCT ENFTRILDSL LDGYDNRLRP GFGGPVTEVK TDIYVTSFGP VSDVEMEYTM DVFFRQTWID KRLKYDGPIE ILRLNNMMVT KVWTPDTFFR NGKKSVSHNM TAPNKLFRIM RNGTILYTMR LTISAECPMR LVDFPMDGHA CPLKFGSYAY PKSEMIYTWT KGPEKSVEVP KESSSLVQYD LIGQTVSSET IKSITGEYIV MTVYFHLRRK MGY

Cross-Reactivity: Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 36-258 of human GABRA4 (NP_000800.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GABRA4

Target: GABRA4 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4))

Alternative Name: GABRA4 (GABRA4 Products)

Synonyms: GABRA4 antibody, Gabra-4 antibody, gamma-aminobutyric acid type A receptor alpha4 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4 antibody, GABRA4 antibody, Gabra4 antibody

Background: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.,GABRA4,Neuroscience,GABRA4

Molecular Weight: 61 kDa

Gene ID: 2557

UniProt: P48169

Pathways: Synaptic Membrane