Recombinant C-Type Lectin Domain Family 4, Member M (CLEC4M) antibody
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- Target See all C-Type Lectin Domain Family 4, Member M (CLEC4M) Antibodies
- C-Type Lectin Domain Family 4, Member M (CLEC4M)
- Antibody Type
- Recombinant Antibody
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- Un-conjugated
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Application
- Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Specificity
- Human CD299, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.
- Characteristics
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OriginalSpeciesName: Mouse
OriginalFormat: IgG1
- Purification
- Purified antibody.
- Immunogen
- CD299
- Clone
- 16E7
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CLEC4M Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % Proclin 300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- C-Type Lectin Domain Family 4, Member M (CLEC4M)
- Alternative Name
- DC-SIGNR (CLEC4M Products)
- Synonyms
- CD209L antibody, CD299 antibody, DC-SIGN2 antibody, DC-SIGNR antibody, DCSIGNR antibody, HP10347 antibody, L-SIGN antibody, LSIGN antibody, CD209B antibody, C-type lectin domain family 4 member M antibody, CLEC4M antibody
- Background
- CD299, C-type lectin domain family 4 member M, CD209 antigen-like protein 1, DC-SIGN-related protein, CLEC4M, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, DC-SIGN2, Liver/lymph node-specific ICAM-3-grabbing non-integrin, L-SIGN
- UniProt
- Q9H2X3
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